Molecular <i>BCR::ABL1</i> Quantification and <i>ABL1</i> Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study

Molecular <i>BCR::ABL1</i> Quantification and <i>ABL1</i> Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study

Chronic myeloid leukemia (CML) is a well-characterized oncological disease in which virtually all patients possess a translocation (9;22) that generates the tyrosine kinase <i>BCR::ABL1</i> protein. This translocation represents one of the milestones in molecular oncology in terms of bot...

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Bibliographic Details
Main Authors: Anelis Maria Marin, Denise Kusma Wosniaki, Heloisa Bruna Soligo Sanchuki, Eduardo Cilião Munhoz, Jeanine Marie Nardin, Gabriela Silva Soares, Dhienifer Caroline Espinace, João Samuel de Holanda Farias, Bruna Veroneze, Luiz Felipe Becker, Guilherme Lima Costa, Olair Carlos Beltrame, Jaqueline Carvalho de Oliveira, Geison Cambri, Dalila Luciola Zanette, Mateus Nóbrega Aoki
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
chronic myeloid leukemia
<i>BCR::ABL1</i>
<i>ABL1</i> mutation
TKI
prognostic
Online Access:https://www.mdpi.com/1422-0067/24/12/10118

Internet

https://www.mdpi.com/1422-0067/24/12/10118

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