Cepharanthine inhibits influenza A virus replication by impairing viral polymerase activity and regulating influenza-induced immune response

Cepharanthine inhibits influenza A virus replication by impairing viral polymerase activity and regulating influenza-induced immune response

Background: Cepharanthine (CEP), a natural bis-benzylisoquinoline alkaloid extracted from the plant Stephania cephalantha Hayata, has been widely used to treat several acute and chronic diseases. However, its antiviral potential against influenza A virus (IAV) infection remains unknown. Purpose: The...

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Bibliographic Details
Main Authors: Yinyan Li, Huiting Sang, Qinxian Mo, Linrui Jiang, Zhixuan Chen, Jinlong Liang, Chunyu Zhang, Zhengyin Zhang, Chenglai Xia, Jie Yang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Phytomedicine Plus
Subjects:
Cepharanthine
Influenza A virus
Viral polymerase activity
Anti-inflammatory
Drug repositioning
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031324000319

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http://www.sciencedirect.com/science/article/pii/S2667031324000319

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