Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

<p>Abstract</p> <p>Background</p> <p>MicroRNAs (miRNAs), some of which function as oncogenes or tumor suppressor genes, are involved in carcinogenesis via regulating cell proliferation and/or cell death. MicroRNA miR-34 was recently found to be a direct target of p53, f...

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Bibliographic Details
Main Authors: DeSano Jeffrey, Zhang Min, Meng Yang, Hao Xinbao, Ji Qing, Fan Daiming, Xu Liang
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/266