Trypanocidal and Anti-Inflammatory Effects of Three <i>ent</i>-Kaurane Diterpenoids from <i>Gymnocoronis spilanthoides</i> var. <i>subcordata</i> (Asteraceae)

Trypanocidal and Anti-Inflammatory Effects of Three <i>ent</i>-Kaurane Diterpenoids from <i>Gymnocoronis spilanthoides</i> var. <i>subcordata</i> (Asteraceae)

Chagas disease, caused by the protozoan <i>Trypanosoma cruzi</i>, affects 6–7 million people worldwide. The dichloromethane extract obtained from the aerial parts of <i>Gymnocoronis spilanthoides</i> var <i>subcordata</i> showed trypanocidal activity in vitro. The...

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Bibliographic Details
Main Authors: Mariana G. Selener, Jimena Borgo, Maria Belen Sarratea, Maria Alicia Delfino, Laura C. Laurella, Natacha Cerny, Jessica Gomez, Mauro Coll, Emilio L. Malchiodi, Augusto E. Bivona, Patricia Barrera, Flavia C. Redko, César A. N. Catalán, Andrés Sánchez Alberti, Valeria P. Sülsen
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceutics
Subjects:
<i>Gymnocoronis</i>
diterpene
natural compounds
<i>ent</i>-kaurane
<i>Trypanosoma cruzi</i>
anti-inflammatory activity
Online Access:https://www.mdpi.com/1999-4923/16/3/415

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https://www.mdpi.com/1999-4923/16/3/415

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