Lack of evidence for increased transcriptional noise in aged tissues

Aging is often associated with a loss of cell type identity that results in an increase in transcriptional noise in aged tissues. If this phenomenon reflects a fundamental property of aging remains an open question. Transcriptional changes at the cellular level are best detected by single-cell RNA s...

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Bibliographic Details
Main Authors: Olga Ibañez-Solé, Alex M Ascensión, Marcos J Araúzo-Bravo, Ander Izeta
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/80380