Functions of IgM fc receptor (FcµR) related to autoimmunity

Functions of IgM fc receptor (FcµR) related to autoimmunity

AbstractUnlike Fc receptors for switched immunoglobulin (Ig) isotypes, Fc receptor for IgM (FcµR) is selectively expressed by lymphocytes. The ablation of the FcµR gene in mice impairs B cell tolerance as evidenced by concomitant production of autoantibodies of IgM and IgG isotypes. In this essay, w...

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Bibliographic Details
Main Authors: Hiromi Kubagawa, Pedram Mahmoudi Aliabadi, Khlowd Al-Qaisi, Peter K. Jani, Kazuhito Honjo, Shozo Izui, Andreas Radbruch, Fritz Melchers
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
Subjects:
Autoantibody
Fc receptor
FCMR deficiency
IgM
tolerance
Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2323563

Internet

https://www.tandfonline.com/doi/10.1080/08916934.2024.2323563

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