New insights into the analgesic properties of the XCL1/XCR1 and XCL1/ITGA9 axes modulation under neuropathic pain conditions - evidence from animal studies

New insights into the analgesic properties of the XCL1/XCR1 and XCL1/ITGA9 axes modulation under neuropathic pain conditions - evidence from animal studies

Recent studies have indicated the involvement of chemokine-C-motif ligand 1 (XCL1) in nociceptive transmission; however, the participation of its two receptors, canonical chemokine-C-motif receptor 1 (XCR1) and integrin alpha-9 (ITGA9), recently recognized as a second receptor, has not been clarifie...

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Bibliographic Details
Main Authors: Agata Ciechanowska, Ewelina Rojewska, Anna Piotrowska, Justyna Barut, Katarzyna Pawlik, Katarzyna Ciapała, Grzegorz Kreiner, Joanna Mika
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
XCL1
XCR1
ITGA9
CCI
astroglia
chemokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058204/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058204/full

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