Natural Schistosoma mansoni Infection in the Wild Reservoir Nectomys squamipes Leads to Excessive Lipid Droplet Accumulation in Hepatocytes in the Absence of Liver Functional Impairment.

Schistosomiasis is a neglected tropical disease of a significant public health impact. The water rat Nectomys squamipes is one of the most important non-human hosts in the schistosomiasis mansoni transmission in Brazil, being considered a wild reservoir. Cellular mechanisms that contribute to the ph...

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Main Authors: Kátia B Amaral, Thiago P Silva, Kássia K Malta, Lívia A S Carmo, Felipe F Dias, Mariana R Almeida, Gustavo F S Andrade, Jefferson S Martins, Roberto R Pinho, Sócrates F Costa-Neto, Rosana Gentile, Rossana C N Melo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5120838?pdf=render