Molecular basis promoting centriole triplet microtubule assembly

Abstract The triplet microtubule, a core structure of centrioles crucial for the organization of centrosomes, cilia, and flagella, consists of unclosed incomplete microtubules. The mechanisms of its assembly represent a fundamental open question in biology. Here, we discover that the ciliopathy prot...

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Bibliographic Details
Main Authors: Yutaka Takeda, Takumi Chinen, Shunnosuke Honda, Sho Takatori, Shotaro Okuda, Shohei Yamamoto, Masamitsu Fukuyama, Koh Takeuchi, Taisuke Tomita, Shoji Hata, Daiju Kitagawa
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46454-x