An analysis of regulatory T-cell and Th-17 cell dynamics during cytomegalovirus replication in solid organ transplant recipients.

BACKGROUND: CMV-specific T-cells are crucial to control CMV-replication post-transplant. Regulatory T-cells (T-regs) are associated with a tolerant immune state and may contribute to CMV-replication. However, T-cell subsets such as T-regs and IL-17 producing T-cells (Th-17) are not well studied in t...

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Bibliographic Details
Main Authors: Adrian Egli, Moacyr Silva, Daire O'Shea, Leticia E Wilson, Aliyah Baluch, Luiz F Lisboa, Luis G Hidalgo, Deepali Kumar, Atul Humar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469568?pdf=render