Effect of Erythropoietin on the Expression of Murine Transferrin Receptor 2

Effect of Erythropoietin on the Expression of Murine Transferrin Receptor 2

Erythropoietin (EPO) downregulates hepcidin expression to increase the availability of iron; the downregulation of hepcidin is mediated by erythroferrone (ERFE) secreted by erythroblasts. Erythroblasts also express transferrin receptor 2 (TFR2); however, the possible role of TFR2 in hepcidin downreg...

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Bibliographic Details
Main Authors: Betty Berezovsky, Martin Báječný, Jana Frýdlová, Iuliia Gurieva, Daniel Wayne Rogalsky, Petr Přikryl, Vít Pospíšil, Emanuel Nečas, Martin Vokurka, Jan Krijt
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
hepcidin
erythroferrone
transferrin receptor
exosomes
Online Access:https://www.mdpi.com/1422-0067/22/15/8209

Internet

https://www.mdpi.com/1422-0067/22/15/8209

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