Risk factors for human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer: an umbrella review and follow-up Mendelian randomisation studies

Abstract Background Persistent infection by oncogenic human papillomavirus (HPV) is necessary although not sufficient for development of cervical cancer. Behavioural, environmental, or comorbid exposures may promote or protect against malignant transformation. Randomised evidence is limited and the...

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Main Authors: Sarah J. Bowden, Triada Doulgeraki, Emmanouil Bouras, Georgios Markozannes, Antonios Athanasiou, Harriet Grout-Smith, Konstantinos S. Kechagias, Laura Burney Ellis, Verena Zuber, Marc Chadeau-Hyam, James M. Flanagan, Konstantinos K. Tsilidis, Ilkka Kalliala, Maria Kyrgiou
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-023-02965-w