Decreased TRPM7 alleviates high glucose-induced renal tubular epithelial cell injury by inhibiting the HMGB1/TLR4 signaling pathway

Decreased TRPM7 alleviates high glucose-induced renal tubular epithelial cell injury by inhibiting the HMGB1/TLR4 signaling pathway

Objective: To explore the regulatory mechanism of transient receptor potential melastatin-7 (TRPM7) in high glucose-induced renal tubular epithelial cell injury. Methods: The expression of TRPM7 in the serum of diabetic nephropathy patients and high glucose-induced HK-2 cells was detected by RT-qPCR...

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Bibliographic Details
Main Authors: Wei Feng, Zheng-Yong Cao, Fu-Min Guan, Hong Chen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
diabetic nephropathy; trpm7; hmgb1/tlr4; high glucose; renal tubular epithelial cell
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=9;spage=393;epage=402;aulast=Feng

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2023;volume=13;issue=9;spage=393;epage=402;aulast=Feng

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