Identification of the Biosynthetic Gene Cluster for the Organoarsenical Antibiotic Arsinothricin

Identification of the Biosynthetic Gene Cluster for the Organoarsenical Antibiotic Arsinothricin

ABSTRACT The soil bacterium Burkholderia gladioli GSRB05 produces the natural compound arsinothricin [2-amino-4-(hydroxymethylarsinoyl) butanoate] (AST), which has been demonstrated to be a broad-spectrum antibiotic. To identify the genes responsible for AST biosynthesis, a draft genome sequence of...

Full description

Bibliographic Details
Main Authors: Adriana E. Galván, Ngozi P. Paul, Jian Chen, Kunie Yoshinaga-Sakurai, Sagar M. Utturkar, Barry P. Rosen, Masafumi Yoshinaga
Format: Article
Language:English
Published: American Society for Microbiology 2021-09-01
Series:Microbiology Spectrum
Subjects:
arsinothricin
organoarsenical antibiotic
biosynthetic gene cluster
Burkholderia gladioli GSRB05
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00502-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.00502-21

Similar Items