Effective Accentuation of Voltage-Gated Sodium Current Caused by Apocynin (4′-Hydroxy-3′-methoxyacetophenone), a Known NADPH-Oxidase Inhibitor

Apocynin (<i>aPO</i>, 4′-Hydroxy-3′-methoxyacetophenone) is a cell-permeable, anti-inflammatory phenolic compound that acts as an inhibitor of NADPH-dependent oxidase (NOX). However, the mechanisms through which <i>aPO</i> can interact directly with plasmalemmal ionic channel...

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Bibliographic Details
Main Authors: Tzu-Hsien Chuang, Hsin-Yen Cho, Sheng-Nan Wu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/9/1146