Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation

Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation

Ionizing radiation (IR) impact cellular and molecular processes that require chromatin remodelling relevant for cellular integrity. However, the cellular implications of ionizing radiation (IR) delivered per time unit (dose rate) are still debated. This study investigates whether the dose rate is re...

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Bibliographic Details
Main Authors: Hildegunn Dahl, Jarle Ballangby, Torstein Tengs, Marcin W. Wojewodzic, Dag M. Eide, Dag Anders Brede, Anne Graupner, Nur Duale, Ann-Karin Olsen
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
gamma radiation
chronic exposure
acute exposure
low dose rate
long-term response
chromatin accessibility
atac-seq
cba mice strain
Online Access:http://dx.doi.org/10.1080/15592294.2023.2193936

Internet

http://dx.doi.org/10.1080/15592294.2023.2193936

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