Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells.

Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells.

Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumorigenesis. Our goal was to evaluate the contribution of Syk and its two splice variants, full length Syk (L) and short isoform Syk (S), in the tumor biology of colorectal cancer cells (CRC). The anal...

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Bibliographic Details
Main Authors: Vincent Denis, Nadège Cassagnard, Maguy Del Rio, Emmanuel Cornillot, Nicole Bec, Christian Larroque, Laura Jeanson, Marta Jarlier, Eve Combès, Bruno Robert, Céline Gongora, Pierre Martineau, Piona Dariavach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0274390&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0274390&type=printable

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