Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases
Over the past 20 years, the concept of mammalian autophagy as a nonselective degradation system has been repudiated, due in part to important discoveries in neurodegenerative diseases, which opened the field of selective autophagy. Protein aggregates and damaged mitochondria represent key pathologic...
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-02-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996118302754 |