In vitro surfactant and perfluorocarbon aerosol deposition in a neonatal physical model of the upper conducting airways.

In vitro surfactant and perfluorocarbon aerosol deposition in a neonatal physical model of the upper conducting airways.

OBJECTIVE: Aerosol delivery holds potential to release surfactant or perfluorocarbon (PFC) to the lungs of neonates with respiratory distress syndrome with minimal airway manipulation. Nevertheless, lung deposition in neonates tends to be very low due to extremely low lung volumes, narrow airways an...

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Bibliographic Details
Main Authors: Estibalitz Goikoetxea, Xabier Murgia, Pablo Serna-Grande, Adolf Valls-i-Soler, Carmen Rey-Santano, Alejandro Rivas, Raúl Antón, Francisco J Basterretxea, Lorena Miñambres, Estíbaliz Méndez, Alberto Lopez-Arraiza, Juan Luis Larrabe-Barrena, Miguel Angel Gomez-Solaetxe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4161382?pdf=render

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http://europepmc.org/articles/PMC4161382?pdf=render

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