Cleavage of SNAP25 and its shorter versions by the protease domain of serotype A botulinum neurotoxin.

Various substrates, catalysts, and assay methods are currently used to screen inhibitors for their effect on the proteolytic activity of botulinum neurotoxin. As a result, significant variation exists in the reported results. Recently, we found that one source of variation was the use of various cat...

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Bibliographic Details
Main Authors: Rahman M Mizanur, Robert G Stafford, S Ashraf Ahmed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095188&type=printable