Selection of RNA aptamers targeting hypoxia in cancer

Selection of RNA aptamers targeting hypoxia in cancer

Hypoxia plays a crucial role in tumorigenesis and drug resistance, and it is recognised as a major factor affecting patient clinical outcome. Therefore, the detection of hypoxic areas within the tumour micro-environment represents a useful way to monitor tumour growth and patients’ responses to trea...

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Bibliographic Details
Main Authors: Silvia Nuzzo, Margherita Iaboni, Maria Luigia Ibba, Anna Rienzo, Domenica Musumeci, Monica Franzese, Giuseppina Roscigno, Alessandra Affinito, Gianluca Petrillo, Cristina Quintavalle, Giuseppe Ciccone, Carla Lucia Esposito, Silvia Catuogno
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
hypoxia
cell-SELEX
aptamer
cancer
detection
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.956935/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.956935/full

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