Assessing methods to quantitatively validate TGFβ-dependent autophagy

Transforming growth factor beta (TGFβ) promotes tumorigenesis by suppressing immune surveillance and inducing epithelial to mesenchymal transition (EMT). TGFβ may augment tumorigenesis by activating autophagy, which protects cancer cells from chemotherapy and promotes invasive and anti-apoptotic pro...

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Bibliographic Details
Main Authors: Charles B. Trelford, Gianni M. Di Guglielmo
Format: Article
Language:English
Published: The Company of Biologists 2020-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/9/11/bio055103