Genetic variants, haplotype determination, and function of novel alleles of CYP2B6 in a Han Chinese population

Genetic variants, haplotype determination, and function of novel alleles of CYP2B6 in a Han Chinese population

Amino acid variants in protein may result in deleterious effects on enzymatic activity. In this study we investigate the DNA variants on activity of CYP2B6 gene in a Chinese Han population for potential use in precision medicine. All exons in CYP2B6 gene from 1483 Chinese Han adults (Zhejiang provin...

Full description

Bibliographic Details
Main Authors: Li-Qun Zhang, Xin-Yue Li, Lian-Guo Chen, Zhe Chen, Ren-Ai Xu, Jian-Chang Qian, Xiao-yang Zhou, Da-Peng Dai, Guo-Xin Hu, Jian-Ping Cai
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
CYP2B6
Genetic variant
Haplotype
Catalytic activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024049831

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024049831

Similar Items