Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation

Summary: Transcriptional regulation of circadian rhythms is essential for lipid metabolic homeostasis, disruptions of which can lead to metabolic diseases. Whether N6-methyladenosine (m6A) mRNA methylation impacts circadian regulation of lipid metabolism is unclear. Here, we show m6A mRNA methylatio...

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Bibliographic Details
Main Authors: Xiang Zhong, Jiayao Yu, Katya Frazier, Xiaocheng Weng, Yi Li, Candace M. Cham, Kyle Dolan, Xiaorong Zhu, Nathaniel Hubert, Yun Tao, Fanfei Lin, Kristina Martinez-Guryn, Yong Huang, Tian Wang, Jianzhao Liu, Chuan He, Eugene B. Chang, Vanessa Leone
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718316723