Metabolomics identifies disturbances in arginine, phenylalanine, and glycine metabolism as differentiating features of exacerbating atopic asthma in children

Metabolomics identifies disturbances in arginine, phenylalanine, and glycine metabolism as differentiating features of exacerbating atopic asthma in children

Background: Asthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying exacerbations in this population. Objective: High-resolution metabolomics analyses were performed to understand the differences in metabolites in children with e...

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Bibliographic Details
Main Authors: Kirsten A. Cottrill, PhD, Joshua D. Chandler, PhD, Seibi Kobara, PT, MPH, Susan T. Stephenson, PhD, Ahmad F. Mohammad, BS, Mallory Tidwell, BSN, RN, Carrie Mason, BS, RRT, Morgan Van Dresser, RN, MSN, James Patrignani, BS, Rishikesan Kamaleswaran, PhD, Anne M. Fitzpatrick, PhD, Jocelyn R. Grunwell, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Arginine
asthma control
asthma exacerbation
asthma in children
glycine
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829323000401

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http://www.sciencedirect.com/science/article/pii/S2772829323000401

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