Development of Methodic Approach to Construction of Recombinant Strain, Producer of the Cholera Toxin B Subunit

Development of Methodic Approach to Construction of Recombinant Strain, Producer of the Cholera Toxin B Subunit

Presented are the results of experiments on the construction of Escherichia coli Top10 (pTrcSuB) strain, perspective for the development of recombinant cholera vaccine for peroral use. The obtained strain possesses inducible expression of cholera toxin B subunit. Peculiarities of cloned gene express...

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Bibliographic Details
Main Authors: D. S. Yanov, S. N. Klinova, A. V. Mironin, I. V. Zhivov, I. P. Pogorelsky, V. I. Drobkov, Yu. N. Feodorov, Ya. A. Kibirev
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2010-08-01
Series:Проблемы особо опасных инфекций
Subjects:
recombinant vaccine
inducible expression
cholera toxin b subunit
vector
Online Access:https://journal.microbe.ru/jour/article/view/568

Internet

https://journal.microbe.ru/jour/article/view/568

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