A study protocol of a randomized phase II trial of perioperative chemoimmunotherapy verses perioperative chemoimmunotherapy plus preoperative chemoradiation for locally advanced gastric (G) or gastroesophageal junction (GEJ) adenocarcinoma: the NeoRacing study

A study protocol of a randomized phase II trial of perioperative chemoimmunotherapy verses perioperative chemoimmunotherapy plus preoperative chemoradiation for locally advanced gastric (G) or gastroesophageal junction (GEJ) adenocarcinoma: the NeoRacing study

Abstract Background Perioperative chemotherapy (ChT) and preoperative chemoradiation (CRT) are both the standard treatments for locally advanced gastric cancer (LAGC). CRT can achieve a higher pathological complete regression (pCR) rate, but whether this higher pCR rate can be transformed into a lon...

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Bibliographic Details
Main Authors: Menglong Zhou, Wang Yang, Yan Xuan, Wei Zou, Yaqi Wang, Zhiyuan Zhang, Jing Zhang, Miao Mo, Changming Zhou, Yuan Liu, Wenming Zhang, Zhaozhen Zhang, Yiping He, Weiwei Weng, Cong Tan, Lei Wang, Dan Huang, Weiqi Sheng, Huanhuan Li, Hui Zhu, Yan Wang, Lijun Shen, Hui Zhang, Juefeng Wan, Guichao Li, Hua Huang, Yanong Wang, Zhen Zhang, Xiaowen Liu, Fan Xia
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Locally advanced gastric cancer
Gastroesophageal junction adenocarcinoma
Preoperative chemoradiation
Immunotherapy
Gastrectomy
Online Access:https://doi.org/10.1186/s12885-022-09786-9

Internet

https://doi.org/10.1186/s12885-022-09786-9

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