Purpurin suppresses Candida albicans biofilm formation and hyphal development.

A striking and clinically relevant virulence trait of the human fungal pathogen Candida albicans is its ability to grow and switch reversibly among different morphological forms. Inhibition of yeast-to-hypha transition in C. albicans represents a new paradigm for antifungal intervention. We have pre...

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Bibliographic Details
Main Authors: Paul Wai-Kei Tsang, H M H N Bandara, Wing-Ping Fong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23226409/?tool=EBI