MicroRNA-142 Inhibits Proliferation and Promotes Apoptosis in Airway Smooth Muscle Cells During Airway Remodeling in Asthmatic Rats via the Inhibition of TGF-β -Dependent EGFR Signaling Pathway

MicroRNA-142 Inhibits Proliferation and Promotes Apoptosis in Airway Smooth Muscle Cells During Airway Remodeling in Asthmatic Rats via the Inhibition of TGF-β -Dependent EGFR Signaling Pathway

Background/Aims: Asthma is a heterogeneous disease characterized by chronic airway inflammation resulting from airway hyper-responsiveness to diverse stimuli. In this study, we investigated whether microRNA-142 (miR-142) expression affects proliferation and apoptosis in airway smooth muscle cells (A...

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Bibliographic Details
Main Authors: Jing Wang, Hu-Shan Wang, Zhen-Bo Su
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
MicroRNA-142
Transforming growth factor-β
EGFR signaling pathway
Asthma
Airway remodeling
Airway smooth muscle cells
Proliferation
Apoptosis
Online Access:https://www.karger.com/Article/FullText/490986

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https://www.karger.com/Article/FullText/490986

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