Collagen pre-strain discontinuity at the bone-Cartilage interface.

Collagen pre-strain discontinuity at the bone-Cartilage interface.

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The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is mechanically-graded and subjected to shear and compressive strains. Changes in the BCU have been linked to osteoarthritis (OA) progression. Here we report existence of a physiological internal strain gradient (pre-...

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Bibliographic Details
Main Authors: Waqas Badar, Husna Ali, Olivia N Brooker, Elis Newham, Tim Snow, Nicholas J Terrill, Gianluca Tozzi, Peter Fratzl, Martin M Knight, Himadri S Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273832

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https://doi.org/10.1371/journal.pone.0273832

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