Utility of primary cells to examine NPC1 receptor expression in Mops condylurus, a potential Ebola virus reservoir.

Utility of primary cells to examine NPC1 receptor expression in Mops condylurus, a potential Ebola virus reservoir.

The significance of the integral membrane protein Niemann-Pick C1 (NPC1) in the ebolavirus entry process has been determined using various cell lines derived from humans, non-human primates and fruit bats. Fruit bats have long been purported as the potential reservoir host for ebolaviruses, however...

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Bibliographic Details
Main Authors: Marcel Bokelmann, Kathryn Edenborough, Nicole Hetzelt, Petra Kreher, Angelika Lander, Andreas Nitsche, Uwe Vogel, Heinz Feldmann, Emmanuel Couacy-Hymann, Andreas Kurth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007952

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https://doi.org/10.1371/journal.pntd.0007952

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