Diet-Induced Hypercholesterolemia Leads to Cardiac Dysfunction and Alterations in the Myocardial Proteome

Diet-Induced Hypercholesterolemia Leads to Cardiac Dysfunction and Alterations in the Myocardial Proteome

Elevated blood cholesterol is a major risk factor for coronary heart disease. Moreover, direct effects on the myocardium also contribute to the adverse effects of hypercholesterolemia. Here, we investigated the effect of hypercholesterolemia on the cardiac proteome. Male Wistar rats were fed with a...

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Bibliographic Details
Main Authors: Márton Richárd Szabó, Márton Pipicz, Márta Sárközy, Bella Bruszel, Zoltán Szabó, Tamás Csont
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
hypercholesterolemia
myocardial proteomics
network analysis
cardiac dysfunction
mitochondrial respiratory chain
contractile proteins
Online Access:https://www.mdpi.com/1422-0067/23/13/7387

Internet

https://www.mdpi.com/1422-0067/23/13/7387

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