A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma

A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma

Abstract Background Programmed cell death protein 1 (PD-1) is a key immune checkpoint that regulates peripheral tolerance and protects against autoimmunity. Programmed death ligand-2 (PD-L2) is a less studied ligand to PD-1 and has yet to be fully explored, especially in pancreatic ductal adenocarci...

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Bibliographic Details
Main Authors: Yiyin Zhang, Jin Xu, Jie Hua, Jiang Liu, Chen Liang, Qingcai Meng, Miaoyan Wei, Bo Zhang, Xianjun Yu, Si Shi
Format: Article
Language:English
Published: BMJ Publishing Group 2019-08-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Pancreatic ductal adenocarcinoma
PD-L2
Immune marker
Prognosis
TGF-β2
Online Access:http://link.springer.com/article/10.1186/s40425-019-0703-0

Internet

http://link.springer.com/article/10.1186/s40425-019-0703-0

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