Inducing Cytotoxicity in Colon Cancer Cells and Suppressing Cancer Stem Cells by Dolasetron and Ketoprofen through Inhibition of RNA Binding Protein PUM1

Inducing Cytotoxicity in Colon Cancer Cells and Suppressing Cancer Stem Cells by Dolasetron and Ketoprofen through Inhibition of RNA Binding Protein PUM1

Clinical trials of new drugs often face a high failure rate of approximately 45 percent due to safety and toxicity concerns. Repurposing drugs with well-established safety profiles becomes crucial in addressing this challenge. Colon cancer ranks as the third most prevalent cancer and the second lead...

Full description

Bibliographic Details
Main Authors: Ravi Gor, Ali Gharib, Priya Dharshini Balaji, Thirumurthy Madhavan, Satish Ramalingam
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxics
Subjects:
post-transcriptional gene regulation
Pumilio1
cancer stem cells
toxicity
dolasetron
ketoprofen
Online Access:https://www.mdpi.com/2305-6304/11/8/669

Internet

https://www.mdpi.com/2305-6304/11/8/669

Similar Items