Synthesis and biological evaluation of mannosyl triazoles and varying the nature of substituents on the terminal phthalimido moiety in the aglycone backbone

In the present study, a facile synthesis of six monovalent α-d-mannoside ligands terminated with phthalimido moiety by Cu(I) catalyzed azide-alkyne cycloaddition reaction (CuAAC) has been achieved. All synthesized ligands were tested for their inhibitory activities against E. coli FimH adhesion usin...

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Bibliographic Details
Main Authors: Hussein Al-Mughaid, Younis Jaradat, Maha Khazaaleh
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622002673