Synthesis and biological evaluation of mannosyl triazoles and varying the nature of substituents on the terminal phthalimido moiety in the aglycone backbone
In the present study, a facile synthesis of six monovalent α-d-mannoside ligands terminated with phthalimido moiety by Cu(I) catalyzed azide-alkyne cycloaddition reaction (CuAAC) has been achieved. All synthesized ligands were tested for their inhibitory activities against E. coli FimH adhesion usin...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622002673 |