The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion

<p>Abstract</p> <p>Background</p> <p>HIV-1 entry into cells is a multifaceted process involving target cell CD4 and the chemokine receptors, CXCR4 or CCR5. The lipid composition of the host cell plays a significant role in the HIV fusion process as it orchestrates the a...

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Bibliographic Details
Main Authors: Puri Anu, Wang Ji, Viard Mathias, Rawat Satinder S, Ablan Sherimay, Blumenthal Robert
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/3/1/104