Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML
Interleukin-12 (IL-12) is a potent cytokine that may be harnessed to treat cancer. To date, nearly 100 IL-12-based clinical trials have been initiated worldwide. Yet systemic administration of IL-12 is toxic. Different strategies are being developed to reduce such toxicities by restricting IL-12 dis...
Huvudupphovsmän: | , , , , , , , , , |
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Materialtyp: | Artikel |
Språk: | English |
Publicerad: |
Elsevier
2016-01-01
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Serie: | Molecular Therapy: Methods & Clinical Development |
Länkar: | http://www.sciencedirect.com/science/article/pii/S2329050117300347 |