A genetically defined asymmetry underlies the inhibitory control of flexor–extensor locomotor movements

A genetically defined asymmetry underlies the inhibitory control of flexor–extensor locomotor movements

V1 and V2b interneurons (INs) are essential for the production of an alternating flexor–extensor motor output. Using a tripartite genetic system to selectively ablate either V1 or V2b INs in the caudal spinal cord and assess their specific functions in awake behaving animals, we find that V1 and V2b...

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Bibliographic Details
Main Authors: Olivier Britz, Jingming Zhang, Katja S Grossmann, Jason Dyck, Jun C Kim, Susan Dymecki, Simon Gosgnach, Martyn Goulding
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
motor behavior
locomotion
mouse genetic
spinal interneurons
Online Access:https://elifesciences.org/articles/04718

Internet

https://elifesciences.org/articles/04718

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