Comparison of 3 optimized delivery strategies for completion of isoniazid-rifapentine (3HP) for tuberculosis prevention among people living with HIV in Uganda: A single-center randomized trial.

<h4>Background</h4>Expanding access to shorter regimens for tuberculosis (TB) prevention, such as once-weekly isoniazid and rifapentine taken for 3 months (3HP), is critical for reducing global TB burden among people living with HIV (PLHIV). Our coprimary hypotheses were that high levels...

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Bibliographic Details
Main Authors: Fred C Semitala, Jillian L Kadota, Allan Musinguzi, Fred Welishe, Anne Nakitende, Lydia Akello, Lynn Kunihira Tinka, Jane Nakimuli, Joan Ritar Kasidi, Opira Bishop, Suzan Nakasendwa, Yeonsoo Baik, Devika Patel, Amanda Sammann, Payam Nahid, Robert Belknap, Moses R Kamya, Margaret A Handley, Patrick Pj Phillips, Anne Katahoire, Christopher A Berger, Noah Kiwanuka, Achilles Katamba, David W Dowdy, Adithya Cattamanchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1004356&type=printable