The mechanism of calcium-induced inhibition of muscle fructose 1,6-bisphosphatase and destabilization of glyconeogenic complex.

The mechanism by which calcium inhibits the activity of muscle fructose 1,6-bisphosphatase (FBPase) and destabilizes its interaction with aldolase, regulating glycogen synthesis from non-carbohydrates in skeletal muscle is poorly understood. In the current paper, we demonstrate evidence that Ca(2+)...

Full description

Bibliographic Details
Main Authors: Dariusz Rakus, Agnieszka Gizak, Andrzej A Kasprzak, Marek Zarzycki, Ewa Maciaszczyk-Dziubinska, Andrzej Dzugaj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795747?pdf=render