Nanoenhancer for improving naked DNA electrotransfection In vivo

Introduction: Electrotransfection (ET) is a non-viral approach widely used for delivery of naked nucleic acids. Its efficiency can be increased in vitro by treatment of cells with various small molecule enhancers. However, these enhancers often fail to improve ET in vivo, presumably due to rapid cle...

Full description

Bibliographic Details
Main Authors: Yifei Wang, Chunxi Wang, Justin Sylvers, Tatiana Segura, Fan Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1181795/full