JQ-1 ameliorates schistosomiasis liver granuloma in mice by suppressing male and female reproductive systems and egg development of Schistosoma japonicum.

Schistosomiasis is a serious and widespread parasitic disease caused by infection with Schistosoma. Because the parasite's eggs are primarily responsible for schistosomiasis dissemination and pathogenesis, inhibiting egg production is a potential approach to control the spread and severity of t...

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Bibliographic Details
Main Authors: Jiaming Tian, Bingxin Dai, Li Gong, Pingping Wang, Han Ding, Siwei Xia, Weice Sun, Cuiping Ren, Jijia Shen, Miao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010661