Contribution and clinical relevance of germline variation to the cancer transcriptome

Abstract Background Somatic alterations in the cancer genome, some of which are associated with changes in gene expression, have been characterized in multiple studies across diverse cancer types. However, less is known about germline variants that influence tumor biology by shaping the cancer trans...

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Bibliographic Details
Main Authors: Bernard Pereira, Emma Labrot, Eric Durand, Joshua M. Korn, Audrey Kauffmann, Catarina D. Campbell
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09757-0