Successful Treatment of Large B-Cell Lymphoma in a Child with Compound Heterozygous Mutation in the <i>ATM</i> Gene

Successful Treatment of Large B-Cell Lymphoma in a Child with Compound Heterozygous Mutation in the <i>ATM</i> Gene

Ataxia-telangiectasia (AT) is a multisystemic neurodegenerative inborn error of immunity (IEI) characterized by DNA repair defect, chromosomal instability, and hypersensitivity to ionizing radiation. Impaired DNA double-strand break repair determines a high risk of developing hematological malignanc...

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Bibliographic Details
Main Authors: Jakub Czarny, Marta Andrzejewska, Olga Zając-Spychała, Elżbieta Latos-Grażyńska, Agata Pastorczak, Kamila Wypyszczak, Aleksandra Szczawińska-Popłonyk, Izabela Niewiadomska-Wojnałowicz, Agnieszka Wziątek, Patrycja Marciniak-Stępak, Michał Dopierała, Jadwiga Małdyk, Katarzyna Jończyk-Potoczna, Katarzyna Derwich
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
ataxia-telangiectasia
LBCL
DNA repair
rituximab
Online Access:https://www.mdpi.com/1422-0067/24/2/1099

Internet

https://www.mdpi.com/1422-0067/24/2/1099

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