Insertion Process of Ceramic Nanoporous Microneedles by Means of a Novel Mechanical Applicator Design

Insertion Process of Ceramic Nanoporous Microneedles by Means of a Novel Mechanical Applicator Design

Arrays of microneedles (MNAs) are integrated in an out-of-plane fashion with a base plate and can serve as patches for the release of drugs and vaccines. We used soft-lithography and micromolding to manufacture ceramic nanoporous (np)MNAs. Failure modes of ceramic npMNAs are as yet poorly understood...

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Bibliographic Details
Main Authors: Xavier H. M. Hartmann, Peter van der Linde, Erik F. G. A. Homburg, Lambert C. A. van Breemen, Arthur M. de Jong, Regina Luttge
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Pharmaceutics
Subjects:
ceramic nanoporous microneedles
soft lithography
micromolding
(trans)dermal drug delivery
microneedle patch
thumb pressure
applicator
skin insertion
fracture force
Online Access:http://www.mdpi.com/1999-4923/7/4/503

Internet

http://www.mdpi.com/1999-4923/7/4/503

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