A Novel Transwell Blood Brain Barrier Model Using Primary Human Cells

Structural alterations and breakdown of the blood brain barrier (BBB) is often a primary or secondary consequence of disease, resulting in brain oedema and the transport of unwanted substances into the brain. It is critical that effective in vitro models are developed to model the in vivo environmen...

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Bibliographic Details
Main Authors: Nicole L. Stone, Timothy J. England, Saoirse E. O’Sullivan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00230/full