A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

Pseudogenes are thought to be inactive gene sequences, but recent evidence of extensive pseudogene transcription raised the question of potential function. Here we discover and characterize the sets of mouse lncRNAs induced by inflammatory signaling via TNFα. TNFα regulates hundreds of lncRNAs, incl...

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Bibliographic Details
Main Authors: Nicole A Rapicavoli, Kun Qu, Jiajing Zhang, Megan Mikhail, Remi-Martin Laberge, Howard Y Chang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00762