Comparison of Antibacterial Activity and Wound Healing in a Superficial Abrasion Mouse Model of Staphylococcus aureus Skin Infection Using Photodynamic Therapy Based on Methylene Blue or Mupirocin or Both

Comparison of Antibacterial Activity and Wound Healing in a Superficial Abrasion Mouse Model of Staphylococcus aureus Skin Infection Using Photodynamic Therapy Based on Methylene Blue or Mupirocin or Both

Background: Antibiotic resistance and impaired wound healing are major concerns in S. aureus superficial skin infections, and new therapies are needed. Antimicrobial photodynamic therapy (aPDT) is a new therapeutic approach for infections, but it also improves healing in many wound models.Objective:...

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Bibliographic Details
Main Authors: Montserrat Pérez, Pilar Robres, Bernardino Moreno, Rosa Bolea, Maria T. Verde, Vanesa Pérez-Laguna, Carmen Aspiroz, Yolanda Gilaberte, Antonio Rezusta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Medicine
Subjects:
S aureus
SKH-1 mice
superficial wound infection
wound healing
photoinactivation
mupirocin
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.673408/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.673408/full

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