Dosage regimen and toxicity risk assessment of linezolid in sepsis patients

Background: Significant alterations in the pharmacokinetic characteristics of linezolid are often seen in sepsis patients. The study aimed to identify a target pharmacokinetics/pharmacodynamics (PK/PD) index of the efficacy of linezolid treatment, and to estimate the optimum dosage regimen of linezo...

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Bibliographic Details
Main Authors: Linjie Dou, Dandan Meng, Yalin Dong, Lihong Chen, Xinyan Han, Di Fan, Haiyan Dong
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220301879