Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders
Abstract Background The development of new aetiological premises, such as the microbiota-gut-brain axis theory, evidences the influence of dietary and nutritional patterns on mental health, affecting the patient's quality of life in terms of physical and cardiovascular health. The aim was to de...
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12888-022-04426-9 |
| _version_ | 1798005061004034048 |
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| author | Alfonso Sevillano-Jiménez Manuel Romero-Saldaña Juan Antonio García-Mellado Lorena Carrascal-Laso María García-Rodríguez Rafael Molina-Luque Guillermo Molina-Recio |
| author_facet | Alfonso Sevillano-Jiménez Manuel Romero-Saldaña Juan Antonio García-Mellado Lorena Carrascal-Laso María García-Rodríguez Rafael Molina-Luque Guillermo Molina-Recio |
| author_sort | Alfonso Sevillano-Jiménez |
| collection | DOAJ |
| description | Abstract Background The development of new aetiological premises, such as the microbiota-gut-brain axis theory, evidences the influence of dietary and nutritional patterns on mental health, affecting the patient's quality of life in terms of physical and cardiovascular health. The aim was to determine the impact of a nutritional programme focused on increasing the intake of prebiotic and probiotic food on cardio-metabolic status in individuals with schizophrenia spectrum disorders in the contextual setting of the SARS-CoV-2 era. Methods A randomised clinical trial (two-arm, double-blind, balanced-block, six-month intervention) was conducted in a group of 50 individuals diagnosed with schizophrenia spectrum disorder during the SARS-CoV-2 confinement period. The control group received conventional dietary counselling on an individual basis. In the intervention group, an individual nutritional education programme with a high content of prebiotics and probiotics (dairy and fermented foods, green leafy vegetables, high-fibre fruit, whole grains, etc.) was established. Data on cardiovascular status were collected at baseline, three and six months. In addition, anthropometric parameters were analysed monthly. Results Forty-four subjects completed follow-up and were analysed. Statistical differences (p < 0.05) were found in all anthropometric variables at baseline and six months of intervention. A 27.4% reduction in the prevalence of metabolic syndrome risk factors in all its components was evidenced, leading to a clinically significant improvement (decrease in cardiovascular risk) in the intervention group at six months. Conclusions The development of a nutritional programme focused on increasing the dietary content of prebiotics and probiotics effectively improves the cardio-metabolic profile in schizophrenia spectrum disorders. Therefore, nursing assumes an essential role in the effectiveness of dietary interventions through nutritional education and the promotion of healthy lifestyles. Likewise, nursing acquires a relevant role in interdisciplinary coordination in confinement contexts. Trial registration The study protocol complied with the Declaration of Helsinki for medical studies; the study received ethical approval from referral Research Ethics Committee in November 2019 (reg. no. 468) and retrospectively registered in clinicaltrials.gov (NCT04366401. First Submitted: 28th April 2020; First Registration: 25th June 2020). |
| first_indexed | 2024-04-11T12:33:17Z |
| format | Article |
| id | doaj.art-5777f39c95af41dc9c40496e4ae76a2f |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-11T12:33:17Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-5777f39c95af41dc9c40496e4ae76a2f2022-12-22T04:23:41ZengBMCBMC Psychiatry1471-244X2022-12-0122111210.1186/s12888-022-04426-9Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disordersAlfonso Sevillano-Jiménez0Manuel Romero-Saldaña1Juan Antonio García-Mellado2Lorena Carrascal-Laso3María García-Rodríguez4Rafael Molina-Luque5Guillermo Molina-Recio6Montilla Community Mental Health Unit. Mental Health Clinical Management Unit. Reina Sofia University Hospital. Avda. AndalucíaDepartment of Nursing, Pharmacology and Physiotherapy, University of Cordoba. Lifestyles, Innovation and Health (GA-16). Maimonides Biomedical Research Institute of Cordoba (IMIBIC)Psychiatry Service, Zamora Provincial Hospital. Zamora Welfare ComplexPsychiatry Service, Zamora Provincial Hospital. Zamora Welfare ComplexDepartment of Nursing and Nutrition, Biomedicine Sciences and Health Faculty, European University. C/Tajo S/NDepartment of Nursing, Pharmacology and Physiotherapy, University of Cordoba. Lifestyles, Innovation and Health (GA-16). Maimonides Biomedical Research Institute of Cordoba (IMIBIC)Department of Nursing, Pharmacology and Physiotherapy, University of Cordoba. Lifestyles, Innovation and Health (GA-16). Maimonides Biomedical Research Institute of Cordoba (IMIBIC)Abstract Background The development of new aetiological premises, such as the microbiota-gut-brain axis theory, evidences the influence of dietary and nutritional patterns on mental health, affecting the patient's quality of life in terms of physical and cardiovascular health. The aim was to determine the impact of a nutritional programme focused on increasing the intake of prebiotic and probiotic food on cardio-metabolic status in individuals with schizophrenia spectrum disorders in the contextual setting of the SARS-CoV-2 era. Methods A randomised clinical trial (two-arm, double-blind, balanced-block, six-month intervention) was conducted in a group of 50 individuals diagnosed with schizophrenia spectrum disorder during the SARS-CoV-2 confinement period. The control group received conventional dietary counselling on an individual basis. In the intervention group, an individual nutritional education programme with a high content of prebiotics and probiotics (dairy and fermented foods, green leafy vegetables, high-fibre fruit, whole grains, etc.) was established. Data on cardiovascular status were collected at baseline, three and six months. In addition, anthropometric parameters were analysed monthly. Results Forty-four subjects completed follow-up and were analysed. Statistical differences (p < 0.05) were found in all anthropometric variables at baseline and six months of intervention. A 27.4% reduction in the prevalence of metabolic syndrome risk factors in all its components was evidenced, leading to a clinically significant improvement (decrease in cardiovascular risk) in the intervention group at six months. Conclusions The development of a nutritional programme focused on increasing the dietary content of prebiotics and probiotics effectively improves the cardio-metabolic profile in schizophrenia spectrum disorders. Therefore, nursing assumes an essential role in the effectiveness of dietary interventions through nutritional education and the promotion of healthy lifestyles. Likewise, nursing acquires a relevant role in interdisciplinary coordination in confinement contexts. Trial registration The study protocol complied with the Declaration of Helsinki for medical studies; the study received ethical approval from referral Research Ethics Committee in November 2019 (reg. no. 468) and retrospectively registered in clinicaltrials.gov (NCT04366401. First Submitted: 28th April 2020; First Registration: 25th June 2020).https://doi.org/10.1186/s12888-022-04426-9Metabolic SyndromeCardiometabolic Risk FactorsSchizophrenia Spectrum and Other Psychotic DisordersNursingSARS-CoV-2 |
| spellingShingle | Alfonso Sevillano-Jiménez Manuel Romero-Saldaña Juan Antonio García-Mellado Lorena Carrascal-Laso María García-Rodríguez Rafael Molina-Luque Guillermo Molina-Recio Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders BMC Psychiatry Metabolic Syndrome Cardiometabolic Risk Factors Schizophrenia Spectrum and Other Psychotic Disorders Nursing SARS-CoV-2 |
| title | Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders |
| title_full | Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders |
| title_fullStr | Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders |
| title_full_unstemmed | Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders |
| title_short | Impact of high prebiotic and probiotic dietary education in the SARS-CoV-2 era: improved cardio-metabolic profile in schizophrenia spectrum disorders |
| title_sort | impact of high prebiotic and probiotic dietary education in the sars cov 2 era improved cardio metabolic profile in schizophrenia spectrum disorders |
| topic | Metabolic Syndrome Cardiometabolic Risk Factors Schizophrenia Spectrum and Other Psychotic Disorders Nursing SARS-CoV-2 |
| url | https://doi.org/10.1186/s12888-022-04426-9 |
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